X-ray Structure of the Rotavirus Protein Involved in Genome Replication and Packaging
نویسندگان
چکیده
Rotavirus, the leading cause of infantile gastroenteritis, with nearly a million deaths worldwide every year, has a spherical shape with many spikes that bind firmly to a host cell. The virus is composed of six structural proteins arranged in three concentric layers, which enclose the viral genome consisting of 11 doublestranded RNA (dsRNA) segments. Each segment codes for at least one protein, except for one segment that codes for two proteins.
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